HPE P07640-B21 16GB PC4-25600AA-R Memory

HPE P07640-B21 16GB Single Rank x4 DDR4-3200 Registered Smart Memory Kit

The HPE P07640-B21 is a 16GB PC4-3200AA-R registered memory kit built for HPE ProLiant Gen10 Plus servers powered by AMD EPYC processors. HPE lists it in the QuickSpecs for the DL385 Gen10 Plus as a single rank x4 DDR4-3200 module with CAS 22 timings.

With eight memory channels per EPYC processor, AMD based Gen10 Plus servers reward filling every channel. A 16GB module lets you do that at a moderate total capacity, which suits storage nodes, VDI hosts and general compute where memory bandwidth matters more than sheer size.

This kit is available New or Refurbished, subject to stock. The warranty and condition for each are shown when you select the option.

Key Features At A Glance

• 16GB registered DDR4 for AMD EPYC ProLiant Gen10 Plus
• Single rank, x4 organisation
• PC4-3200AA-R rating, CAS 22
• ECC and HPE SmartMemory
• Good fit for populating all eight channels per processor
• New or Refurbished, subject to stock

Speed At One And Two DIMMs Per Channel

The DL385 Gen10 Plus QuickSpecs are clear on this point: 3200 MT/s memory runs at 3200 MT/s with one DIMM per channel, and drops to 2933 MT/s when two DIMMs share a channel. The server has 32 slots, 16 per processor across eight channels.

So a two processor server with sixteen of these modules, one per channel, gives 256GB at full 3200 MT/s. Filling all 32 slots doubles that to 512GB but at 2933 MT/s. If you need more capacity at full speed, a larger module per channel may be the better choice.

x4 And x8 Cannot Be Mixed

HPE produced two 16GB DDR4-3200 kits for AMD Gen10 Plus. P07640-B21 is single rank x4, while P07642-B21 is dual rank x8. The DL385 Gen10 Plus QuickSpecs state that mixing x4 and x8 memory is not allowed, and that RDIMMs cannot be combined with LRDIMMs or 3DS LRDIMMs.

Before ordering, read the label on an installed module. If it shows 1Rx4, this kit matches. If it shows 2Rx8, choose P07642-B21 instead, or replace the full set.

EPYC 7002 And The Gen10 Plus v2 Models

The original DL385 Gen10 Plus is built for AMD EPYC 7002 Series processors, and HPE states that EPYC 7003 Series processors cannot be supported in that system. HPE later released Gen10 Plus v2 servers for the newer chips. P07640-B21 appears in the QuickSpecs for the original DL385 Gen10 Plus, so if you run a v2 server, check its own QuickSpecs memory list before ordering. Reading the model name on the front label or in iLO will tell you which version you have.

New P07640-B21 Memory

New stock is unused. The warranty and packaging information for it are shown on selection.

Refurbished P07640-B21 Memory

Refurbished stock is previously used and costs less. The condition notes and warranty for this option appear when you choose it.

P07640-B21 Technical Specifications

AMD Gen10 Plus Server Compatibility

• HPE ProLiant DL385 Gen10 Plus (AMD EPYC 7002, listed in HPE QuickSpecs)
• HPE ProLiant DL325 Gen10 Plus
• HPE ProLiant DL365 Gen10 Plus
• HPE DX385 Gen10 Plus

Models other than the DL385 Gen10 Plus come from spares cross-references. This kit is not listed for Intel Gen10 Plus servers, which use their own DDR4-3200 kits.

Related AMD Gen10 Plus Memory

• If your modules are 2Rx8, you need the HPE P07642-B21 16GB dual rank x8 kit.
• Double the capacity with the HPE P07646-B21 32GB DDR4-3200 kit.
• For high capacity builds, see the HPE P07650-B21 64GB DDR4-3200 kit.
• The 32GB service spare is listed as HPE P20503-001 32GB DDR4-3200 memory.
• Compare all sizes in our server memory kit category.
• Looking for other parts? Browse our HPE product listings.

Confirming The Match

• The module label should show 16GB 1Rx4 PC4-3200AA-R.
• Look for P07640-B21, P20500-001 or P11442-191.
• Your server should be an AMD EPYC based Gen10 Plus model.
• No x8 or load reduced modules should be fitted alongside it.

Buying P07640-B21 in the UK

We deliver HPE memory to UK customers, with the delivery options shown at checkout. If you need help choosing between the x4 and x8 kits, contact us with your server model, serial number and DIMM label details.

Frequently Asked Questions

Does P07640-B21 work in Intel based Gen10 Plus servers?

It is listed for AMD EPYC Gen10 Plus servers such as the DL385 Gen10 Plus. Intel Gen10 Plus servers such as the DL380 Gen10 Plus use their own DDR4-3200 kits, so check your QuickSpecs.

Why does my DL385 Gen10 Plus report 2933 MT/s with this memory?

HPE states that memory drops to 2933 MT/s when two DIMMs are populated per channel. With one DIMM per channel it runs at 3200 MT/s.

Can I mix P07640-B21 with P07642-B21 modules?

No. P07640-B21 is x4 and P07642-B21 is x8, and HPE does not allow x4 and x8 memory to be mixed in the DL385 Gen10 Plus.

How do I find the warranty for this 16GB kit?

Choose New or Refurbished on the product page and the warranty for that condition is displayed.

Can I have P07640-B21 delivered to a UK data centre or office?

Yes. We deliver to UK addresses, and the available shipping options are shown at checkout.